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Development and In Vitro Evaluation of 2-Methoxyestradiol Loaded Polymeric Micelles for Enhancing Anticancer Activities in Prostate Cancer

The present study aimed to formulate and optimize 2ME-loaded PMs (2ME-PMs) for enhancing the anticancer activity of 2ME in prostate cancer (PC). The 2ME-PMs were formulated using PEG-PLGA (PL), Tween 80 (TW80), and alpha-lipoic acid (ALA). The optimization was carried out using a Box-Behnken design...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Polymers (Basel)
Hauptverfasser: Alhakamy, Nabil A., Ahmed, Osama A. A., Fahmy, Usama A., Md, Shadab
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998642/
https://ncbi.nlm.nih.gov/pubmed/33805675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym13060884
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