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Reduced Interaction of Aggregated α-Synuclein and VAMP2 by Environmental Enrichment Alleviates Hyperactivity and Anxiety in a Model of Parkinson’s Disease

Parkinson’s disease (PD) is a prevalent motor disease caused by the accumulation of mutated α-synuclein (α-Syn); however, its early stages are also characterized by non-motor symptoms, such as olfactory loss, cognitive decline, depression, and anxiety. The therapeutic effects of environmental enrich...

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Publicat a:Genes (Basel)
Autors principals: Kim, Kyungri, Wi, Soohyun, Seo, Jung Hwa, Pyo, Soonil, Cho, Sung-Rae
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998569/
https://ncbi.nlm.nih.gov/pubmed/33801790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12030392
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