Intra-articular injection of human umbilical cord mesenchymal stem cells ameliorates monosodium iodoacetate-induced osteoarthritis in rats by inhibiting cartilage degradation and inflammation

AIMS: This study aimed to investigate whether human umbilical cord mesenchymal stem cells (UC-MSCs) can prevent articular cartilage degradation and explore the underlying mechanisms in a rat osteoarthritis (OA) model induced by monosodium iodoacetate (MIA). METHODS: Human UC-MSCs were characterized...

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Bibliographische Detailangaben
Veröffentlicht in:Bone Joint Res
Hauptverfasser: Zhang, Quan, Xiang, E., Rao, Wei, Zhang, Ya Qi, Xiao, Cui Hong, Li, Chang Yong, Han, Bing, Wu, Dongcheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: The British Editorial Society of Bone & Joint Surgery 2021
Schlagworte:
Arthritis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998343/
https://ncbi.nlm.nih.gov/pubmed/33739851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.103.BJR-2020-0206.R2
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