Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites

With increased human presence in space, bone loss and fractures will occur. Thrombopoietin (TPO) is a recently patented bone healing agent. Here, we investigated the systemic effects of TPO on mice subjected to spaceflight and sustaining a bone fracture. Forty, 9-week-old, male, C57BL/6 J were divid...

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Detalhes bibliográficos
Publicado no:NPJ Microgravity
Main Authors: Zamarioli, Ariane, Campbell, Zachery R., Maupin, Kevin A., Childress, Paul J., Ximenez, Joao P. B., Adam, Gremah, Chakraborty, Nabarun, Gautam, Aarti, Hammamieh, Rasha, Kacena, Melissa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997973/
https://ncbi.nlm.nih.gov/pubmed/33772025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41526-021-00140-0
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