Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway

The objective of this study was to investigate the molecular response to damage at the blood-brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment in central nervous system (CNS) pathologies in which the BBB is compromised. We have used a human, stem-cell deri...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Rand, Daniel, Ravid, Orly, Atrakchi, Dana, Israelov, Hila, Bresler, Yael, Shemesh, Chen, Omesi, Liora, Liraz-Zaltsman, Sigal, Gosselet, Fabien, Maskrey, Taber S., Schnaider Beeri, Michal, Wipf, Peter, Cooper, Itzik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997362/
https://ncbi.nlm.nih.gov/pubmed/33670876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030311
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