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Therapeutic Potential of Targeting Plasminogen Activator Inhibitor-1 in COVID-19

Latest research shows that SERPINE1 overexpression has an important role in Coronavirus 2019 (COVID-19)-associated coagulopathy leading to acute respiratory distress syndrome (ARDS). However, ways to target this protein remain elusive. In this forum, we discuss recent evidence linking SERPINE1 with...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Kellici, Tahsin F., Pilka, Ewa S., Bodkin, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997307/
https://ncbi.nlm.nih.gov/pubmed/33867130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2021.03.006
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