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A unified framework for inferring the multi-scale organization of chromatin domains from Hi-C

Chromosomes are giant chain molecules organized into an ensemble of three-dimensional structures characterized with its genomic state and the corresponding biological functions. Despite the strong cell-to-cell heterogeneity, the cell-type specific pattern demonstrated in high-throughput chromosome c...

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Bibliografski detalji
Izdano u:PLoS Comput Biol
Glavni autori: Bak, Ji Hyun, Kim, Min Hyeok, Liu, Lei, Hyeon, Changbong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7997044/
https://ncbi.nlm.nih.gov/pubmed/33724986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008834
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