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Generation and Breeding of EGFP-Transgenic Marmoset Monkeys: Cell Chimerism and Implications for Disease Modeling

Genetic modification of non-human primates (NHP) paves the way for realistic disease models. The common marmoset is a NHP species increasingly used in biomedical research. Despite the invention of RNA-guided nucleases, one strategy for protein overexpression in NHP is still lentiviral transduction....

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Publicat a:Cells
Autors principals: Drummer, Charis, Vogt, Edgar-John, Heistermann, Michael, Roshani, Berit, Becker, Tamara, Mätz-Rensing, Kerstin, Kues, Wilfried A., Kügler, Sebastian, Behr, Rüdiger
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996964/
https://ncbi.nlm.nih.gov/pubmed/33673402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030505
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