Activated Protein C (APC) and 3K3A-APC-Induced Regression of Choroidal Neovascularization (CNV) Is Accompanied by Vascular Endothelial Growth Factor (VEGF) Reduction

The activated protein C (APC) ability to inhibit choroidal neovascularization (CNV) growth and leakage was recently shown in a murine model. A modified APC, 3K3A-APC, was designed to reduce anticoagulant activity while maintaining full cytoprotective properties, thus diminishing bleeding risk. We ai...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Livnat, Tami, Weinberger, Yehonatan, Fernández, José A., Bashir, Alaa, Ben-David, Gil, Palevski, Dahlia, Levy-Mendelovich, Sarina, Kenet, Gili, Budnik, Ivan, Nisgav, Yael, Griffin, John H., Weinberger, Dov
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996919/
https://ncbi.nlm.nih.gov/pubmed/33652861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030358
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