Nrf2 Signaling Pathway in Chemoprotection and Doxorubicin Resistance: Potential Application in Drug Discovery

Doxorubicin (DOX) is extensively applied in cancer therapy due to its efficacy in suppressing cancer progression and inducing apoptosis. After its discovery, this chemotherapeutic agent has been frequently used for cancer therapy, leading to chemoresistance. Due to dose-dependent toxicity, high conc...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Antioxidants (Basel)
Päätekijät: Mirzaei, Sepideh, Zarrabi, Ali, Hashemi, Farid, Zabolian, Amirhossein, Saleki, Hossein, Azami, Negar, Hamzehlou, Soodeh, Farahani, Mahdi Vasheghani, Hushmandi, Kiavash, Ashrafizadeh, Milad, Khan, Haroon, Kumar, Alan Prem
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996755/
https://ncbi.nlm.nih.gov/pubmed/33652780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10030349
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