Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC)

BACKGROUND: Currently available biomarkers are imperfect in their ability to predict responses to the multiple first-line treatment options available for patients with advanced non-small cell lung cancer (NSCLC). Having an early pharmacodynamic marker of treatment resistance may help redirect patien...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Ricciuti, Biagio, Jones, Greg, Severgnini, Mariano, Alessi, Joao V, Recondo, Gonzalo, Lawrence, Marissa, Forshew, Tim, Lydon, Christine, Nishino, Mizuki, Cheng, Michael, Awad, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2021
Schlagworte:
Immunotherapy Biomarkers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996662/
https://ncbi.nlm.nih.gov/pubmed/33771889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001504
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