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Synthesis, Cytotoxicity and Anti-Proliferative Activity against AGS Cells of New 3(2H)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker

Novel twenty-three 3(2H)-pyridazinone derivatives were designed and synthesized based on the chemical requirements related to the anti-proliferative effects previously demonstrated within this scaffold. The introduction of a piperazinyl linker between the pyridazinone nucleus and the additional (un)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Pharmaceuticals (Basel)
Main Authors: Alagöz, Mehmet Abdullah, Özdemir, Zeynep, Uysal, Mehtap, Carradori, Simone, Gallorini, Marialucia, Ricci, Alessia, Zara, Susi, Mathew, Bijo
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996573/
https://ncbi.nlm.nih.gov/pubmed/33668893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14030183
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