The effect of denosumab on pedicle screw fixation: a prospective 2-year longitudinal study using finite element analysis

BACKGROUND: Pedicle screw loosening is a major complication following spinal fixation associated with osteoporosis in elderly. However, denosumab is a promising treatment in patients with osteoporosis. The effect of denosumab on pedicle screw fixation is unknown. Therefore, we investigated whether d...

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Bibliographic Details
Published in:J Orthop Surg Res
Main Authors: Tani, Soji, Ishikawa, Koji, Kudo, Yoshifumi, Tsuchiya, Koki, Matsuoka, Akira, Maruyama, Hiroshi, Emori, Haruka, Yamamura, Ryo, Hayakawa, Chikara, Sekimizu, Masaya, Oshita, Yusuke, Ozawa, Tomoyuki, Shirahata, Toshiyuki, Nagai, Takashi, Toyone, Tomoaki, Inagaki, Katsunori
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995779/
https://ncbi.nlm.nih.gov/pubmed/33771178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02360-2
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