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A new algorithm to train hidden Markov models for biological sequences with partial labels

BACKGROUND: Hidden Markov models (HMM) are a powerful tool for analyzing biological sequences in a wide variety of applications, from profiling functional protein families to identifying functional domains. The standard method used for HMM training is either by maximum likelihood using counting when...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Li, Jiefu, Lee, Jung-Youn, Liao, Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995745/
https://ncbi.nlm.nih.gov/pubmed/33771095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04080-0
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