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Mutant glucocorticoid receptor binding elements on the interleukin-6 promoter regulate dexamethasone effects

BACKGROUND: Glucocorticoids (GCs) have been extensively used as essential modulators in clinical infectious and inflammatory diseases. The GC receptor (GR) is a transcription factor belonging to the nuclear receptor family that regulates anti-inflammatory processes and releases pro-inflammatory cyto...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Chang, Wen-Teng, Hong, Ming-Yuan, Chen, Chien-Liang, Hwang, Chi-Yuan, Tsai, Cheng-Chieh, Chuang, Chia-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7995394/
https://ncbi.nlm.nih.gov/pubmed/33771121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-021-00413-z
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