Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

Prion diseases are distinguished by long pre-clinical incubation periods during which prions actively propagate in the brain and cause neurodegeneration. In the pre-clinical stage, we hypothesize that upon prion infection, transcriptional changes occur that can lead to early neurodegeneration. A lon...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Cheng, Lesley, Quek, Camelia, Li, Xia, Bellingham, Shayne A., Ellett, Laura J., Shambrook, Mitch, Zafar, Saima, Zerr, Inga, Lawson, Victoria A., Hill, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994852/
https://ncbi.nlm.nih.gov/pubmed/33767334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01868-x
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