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Degradation of insulin amyloid by antibiotic minocycline and formation of toxic intermediates
Insulin balls, localized insulin amyloids formed at subcutaneous insulin-injection sites in patients with diabetes, cause poor glycemic control owing to impairments in insulin absorption. Our previous study has shown that some insulin balls are cytotoxic, but others are not, implying amyloid polymor...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7994847/ https://ncbi.nlm.nih.gov/pubmed/33767265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86001-y |
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