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Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers

The formula of a standardized extract of Centella asiatica (ECa 233) was modified to improve its dissolution, with implications for pharmacokinetics and metabolomic profile. This study aimed to understand the resultant changes in disposition kinetics of ECa 233 and alterations to human metabolome af...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Songvut, Phanit, Chariyavilaskul, Pajaree, Khemawoot, Phisit, Tansawat, Rossarin
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994819/
https://ncbi.nlm.nih.gov/pubmed/33767223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86267-2
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