Genotoxic and oxidative effect of duloxetine on mouse brain and liver tissues

We evaluated the duloxetine DNA damaging capacity utilizing the comet assay applied to mouse brain and liver cells, as well as its DNA, lipid, protein, and nitric oxide oxidative potential in the same cells. A kinetic time/dose strategy showed the effect of 2, 20, and 200 mg/kg of the drug administe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Álvarez-González, Isela, Camacho-Cantera, Scarlett, Gómez-González, Patricia, Barrón, Michael J. Rendón, Morales-González, José A., Madrigal-Santillán, Eduardo O., Paniagua-Pérez, Rogelio, Madrigal-Bujaidar, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994804/
https://ncbi.nlm.nih.gov/pubmed/33767322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86366-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados