Inhibiting Monoacylglycerol Lipase Suppresses RANKL-Induced Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss

Osteoporosis is a common chronic metabolic bone disease characterized by reduced trabecular bone and increased bone fragility. Monoacylglycerol lipase (MAGL) is a lipolytic enzyme to catalyze the hydrolysis of monoglycerides and specifically degrades the 2-arachidonoyl glycerol (2-AG). Previous stud...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Liu, Hui, Zhou, Chuankun, Qi, Dahu, Gao, Yutong, Zhu, Meipeng, Tao, Tenghui, Sun, Xuying, Xiao, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994615/
https://ncbi.nlm.nih.gov/pubmed/33777947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.640867
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