Decreased Intestinal Microbiome Diversity in Pediatric Sepsis: A Conceptual Framework for Intestinal Dysbiosis to Influence Immunometabolic Function

OBJECTIVES: The intestinal microbiome can modulate immune function through production of microbial-derived short-chain fatty acids. We explored whether intestinal dysbiosis in children with sepsis leads to changes in microbial-derived short-chain fatty acids in plasma and stool that are associated w...

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Detalhes bibliográficos
Publicado no:Crit Care Explor
Main Authors: Weiss, Scott L., Bittinger, Kyle, Lee, Jung-Jin, Friedman, Elliot S., Mattei, Lisa M., Graham, Kathryn, Zhang, Donglan, Bush, Jeny, Balamuth, Fran, McGowan, Francis X., Bushman, Frederic D., Baldassano, Robert N., Wu, Gary D., Wallace, Douglas C., Collman, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Original Clinical Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7994045/
https://ncbi.nlm.nih.gov/pubmed/33786436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCE.0000000000000360
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