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Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133(+) cells

Hyperglycemia is one of the major health concern in many parts of the world. One of the serious complications of high glucose levels is diabetic nephropathy. The preliminary microarray study performed on primary human renal tubular epithelial (hRTE) cells exposed to high glucose levels showed a sign...

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Vydáno v:PLoS One
Hlavní autoři: Shrestha, Swojani, Singhal, Sandeep, Sens, Donald A., Somji, Seema, Davis, Bethany A., Guyer, Rachel, Breen, Spencer, Kalonick, Matthew, Garrett, Scott H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993790/
https://ncbi.nlm.nih.gov/pubmed/33764985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248241
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