Increased sCD163 and sCD14 Plasmatic Levels and Depletion of Peripheral Blood Pro-Inflammatory Monocytes, Myeloid and Plasmacytoid Dendritic Cells in Patients With Severe COVID-19 Pneumonia

BACKGROUND: Emerging evidence argues that monocytes, circulating innate immune cells, are principal players in COVID-19 pneumonia. The study aimed to investigate the role of soluble (s)CD163 and sCD14 plasmatic levels in predicting disease severity and characterize peripheral blood monocytes and den...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Zingaropoli, Maria Antonella, Nijhawan, Parni, Carraro, Anna, Pasculli, Patrizia, Zuccalà, Paola, Perri, Valentina, Marocco, Raffaella, Kertusha, Blerta, Siccardi, Guido, Del Borgo, Cosmo, Curtolo, Ambrogio, Ajassa, Camilla, Iannetta, Marco, Ciardi, Maria Rosa, Mastroianni, Claudio Maria, Lichtner, Miriam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993197/
https://ncbi.nlm.nih.gov/pubmed/33777012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.627548
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