Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of ‘epidrugs’

Testicular germ cell tumours (TGCTs) are heterogeneous neoplasms mostly affecting young-adult men. Despite high survival rates, some patients with disseminated disease acquire cisplatin resistance, entailing the need for less toxic therapies. Epigenetic alterations constitute an important feature of...

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Detalles Bibliográficos
Publicado en:Epigenetics
Autores principales: Cardoso, Ana Rita, Lobo, João, Miranda-Gonçalves, Vera, Henrique, Rui, Jerónimo, Carmen
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993192/
https://ncbi.nlm.nih.gov/pubmed/32749176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1805682
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