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CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition

Although CDKN2A is well-known as a susceptibility gene for melanoma and pancreatic cancer, germline variants have also been anecdotally associated with a broader range of neoplasms including neural system tumors, head and neck squamous cell carcinomas, breast carcinomas, as well as sarcomas. The CDK...

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Detalhes bibliográficos
Publicado no:Hered Cancer Clin Pract
Main Authors: Chan, Sock Hoai, Chiang, Jianbang, Ngeow, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992806/
https://ncbi.nlm.nih.gov/pubmed/33766116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13053-021-00178-x
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