Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer

BACKGROUND: Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect circulating tumor-derived EVs (ctEVs) by mutant mRNA transcripts (EV-RNA) in plasma of patients with solid cancers...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Vitale, Silvia R., Helmijr, Jean A., Gerritsen, Marjolein, Coban, Hicret, van Dessel, Lisanne F., Beije, Nick, van der Vlugt-Daane, Michelle, Vigneri, Paolo, Sieuwerts, Anieta M., Dits, Natasja, van Royen, Martin E., Jenster, Guido, Sleijfer, Stefan, Lolkema, Martijn, Martens, John W. M., Jansen, Maurice P. H. M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992353/
https://ncbi.nlm.nih.gov/pubmed/33761899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08007-z
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