A Dose-Finding Trial for Hyperthermic Intraperitoneal Cisplatin in Gynecological Cancer Patients Receiving Hyperthermic Intraperitoneal Chemotherapy

Background: To identify the maximum tolerated dose (MTD) of hyperthermic intraperitoneal cisplatin at 43°C among gynecological cancer patients. Methods: In this Phase I dose-finding trial, Bayesian optimal interval (BOIN) design was used. We sought to explore the MTD with a target dose-limiting toxi...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Chan, Chui-ying, Li, Hui, Wu, Miao-fang, Liu, Chang-hao, Lu, Huai-wu, Lin, Zhong-qiu, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7991782/
https://ncbi.nlm.nih.gov/pubmed/33777754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.616264
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