Identifying the major lactate transporter of Toxoplasma gondii tachyzoites

Toxoplasma gondii and Plasmodium falciparum parasites both extrude l-lactate, a byproduct of glycolysis. The P. falciparum Formate Nitrite Transporter, PfFNT, mediates l-lactate transport across the plasma membrane of P. falciparum parasites and has been validated as a drug target. The T. gondii gen...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zeng, Joy M., Hapuarachchi, Sanduni V., Shafik, Sarah H., Martin, Rowena E., Kirk, Kiaran, van Dooren, Giel G., Lehane, Adele M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7991638/
https://ncbi.nlm.nih.gov/pubmed/33762657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86204-3
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