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Chondrogenic and BMP-4 primings confer osteogenesis potential to human cord blood mesenchymal stromal cells delivered with biphasic calcium phosphate ceramics

Bone marrow mesenchymal stem/stromal cells (BMSCs) show great promise for bone repair, however they are isolated by an invasive bone marrow harvest and their regenerative potential decreases with age. Conversely, cord blood can be collected non-invasively after birth and contains MSCs (CBMSCs) that...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Brennan, Meadhbh Á., Barilani, Mario, Rusconi, Francesco, de Lima, Julien, Vidal, Luciano, Lavazza, Cristiana, Lazzari, Lorenza, Giordano, Rosaria, Layrolle, Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7991626/
https://ncbi.nlm.nih.gov/pubmed/33762629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86147-9
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