Seipin Deficiency Accelerates Heart Failure Due to Calcium Handling Abnormalities and Endoplasmic Reticulum Stress in Mice

Seipin deficiency can induce hypertrophic cardiomyopathy and heart failure, which often leads to death in humans. To explore the effects and the possible mechanisms of Seipin deficiency in myocardial remodeling, Seipin knockout (SKO) mice underwent transverse aortic constriction (TAC) for 12 weeks....

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Bibliografiske detaljer
Udgivet i:Front Cardiovasc Med
Main Authors: Wu, Xiaoyue, Liu, Xuejing, Wang, Huan, Zhou, Zihao, Yang, Chengzhi, Li, Zijian, Zhang, Youyi, Shi, XiaoLu, Zhang, Ling, Wang, Yuhui, Xian, Xunde, Liu, George, Huang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cardiovascular Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990891/
https://ncbi.nlm.nih.gov/pubmed/33778025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.644128
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