A requirement for p120-catenin in the metastasis of invasive ductal breast cancer

We report here the effects of targeted p120-catenin (encoded by CTNND1; hereafter denoted p120) knockout (KO) in a PyMT mouse model of invasive ductal (mammary) cancer (IDC). Mosaic p120 ablation had little effect on primary tumor growth but caused significant pro-metastatic alterations in the tumor...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Kurley, Sarah J., Tischler, Verena, Bierie, Brian, Novitskiy, Sergey V., Noske, Aurelia, Varga, Zsuzsanna, Zürrer-Härdi, Ursina, Brandt, Simone, Carnahan, Robert H., Cook, Rebecca S., Muller, William J., Richmond, Ann, Reynolds, Albert B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990862/
https://ncbi.nlm.nih.gov/pubmed/33097605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.250639
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