A blocking antibody against canine CSF-1R maturated by limited CDR mutagenesis

CSF-1R is a receptor mostly associated with the mononuclear phagocytic system. However, its expression within tumors has been linked with poor prognosis in both humans and dogs. Accordingly, several reports have demonstrated the beneficial effects of blocking CSF-1R in model systems of cancer. In th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antib Ther
Auteurs principaux: Beirão, Breno C B, Raposo, Teresa P, Imamura, Louise M, Ingberman, Max, Hupp, Ted, Vojtěšek, Bořivoj, Argyle, David J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Original Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990251/
https://ncbi.nlm.nih.gov/pubmed/33937625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbaa018
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