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Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity

CCR2 is the major chemokine receptor that regulates appropriate trafficking of inflammatory monocytes, but the role of this chemokine receptor and its ligands during primary and secondary infection with intracellular infections remains incompletely understood. Here we used murine infection with the...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Kurtz, Sherry L., De Pascalis, Roberto, Meierovics, Anda I., Elkins, Karen L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7990183/
https://ncbi.nlm.nih.gov/pubmed/33760886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249142
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