COVID-19: disease pathways and gene expression changes predict methylprednisolone can improve outcome in severe cases

MOTIVATION: COVID-19 has several distinct clinical phases: a viral replication phase, an inflammatory phase, and in some patients, a hyper-inflammatory phase. High mortality is associated with patients developing cytokine storm syndrome. Treatment of hyper-inflammation in these patients using existi...

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Vydáno v:Bioinformatics
Hlavní autoři: Draghici, Sorin, Nguyen, Tuan-Minh, Sonna, Larry A, Ziraldo, Cordelia, Vanciu, Radu, Fadel, Raef, Morrison, Austin, Kenney, Rachel M, Alangaden, George, Ramesh, Mayur, Mor, Gil
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7989618/
https://ncbi.nlm.nih.gov/pubmed/33693506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btab163
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