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Alpha-1 antitrypsin (AAT) augmentation therapy in individuals with the PI*MZ genotype: a pro/con debate on a working hypothesis

Alpha-1 antitrypsin deficiency (AATD) is a significantly under-diagnosed genetic condition caused by reduced levels and/or functionality of alpha-1 antitrypsin (AAT), predisposing individuals to lung, liver or other systemic diseases. The management of individuals with the PI*MZ genotype, characteri...

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Détails bibliographiques
Publié dans:BMC Pulm Med
Auteurs principaux: Barjaktarevic, Igor, Miravitlles, Marc
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7989144/
https://ncbi.nlm.nih.gov/pubmed/33757485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-021-01466-x
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