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Cyclin-dependent kinase 4/6 inhibitors require an arcuate-to-paraventricular hypothalamus melanocortin circuit to treat diet-induced obesity

The arcuate nucleus (ARC) of the hypothalamus comprises two antagonistic neuron populations critical for energy balance, namely, the anorexigenic pro-opiomelanocortin (POMC) and the orexigenic agouti-related peptide (AgRP) neurons that act as agonists and antagonists, respectively, for neurons expre...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Endocrinol Metab
Asıl Yazarlar: Iqbal, Niloy Jafar, Schwartz, Gary J., Zhao, Hongling, Zhu, Liang, Chua, Streamson
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988782/
https://ncbi.nlm.nih.gov/pubmed/33356996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00386.2020
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