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Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation

Myeloid-derived cells, in particular macrophages, are increasingly recognized as critical regulators of the balance of immunity and tolerance. However, whether they initiate autoimmune disease or perpetuate disease progression in terms of epiphenomena remains undefined. Here, we show that depletion...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Dis Model Mech
Hauptverfasser: Dobosz, Ewelina, Lorenz, Georg, Ribeiro, Andrea, Würf, Vivian, Wadowska, Marta, Kotlinowski, Jerzy, Schmaderer, Christoph, Potempa, Jan, Fu, Mingui, Koziel, Joanna, Lech, Maciej
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988765/
https://ncbi.nlm.nih.gov/pubmed/33737335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.047589
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