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FLI1 and ERG protein degradation is regulated via Cathepsin B lysosomal pathway in human dermal microvascular endothelial cells

OBJECTIVES: Friend leukemia integration 1 and erythroblast transformation‐specific, important regulators of endothelial cell homeostasis, are reduced in microvascular endothelial cells in scleroderma patients, and their deficiency has been implicated in disease pathogenesis. The goal of this study w...

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Detalhes bibliográficos
Publicado no:Microcirculation
Main Authors: Mazzotta, Celestina, Marden, Grace, Farina, Alessandra, Bujor, Andreea, Trojanowski, Marcin A., Trojanowska, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988617/
https://ncbi.nlm.nih.gov/pubmed/32979864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12660
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