Identification of deleterious recessive haplotypes and candidate deleterious recessive mutations in Japanese Black cattle

Intensive use of a few elite sires has increased the risk of the manifestation of deleterious recessive traits in cattle. Substantial genotyping data gathered using single-nucleotide polymorphism (SNP) arrays have identified the haplotypes with homozygous deficiency, which may compromise survival. W...

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Udgivet i:Sci Rep
Main Authors: Sasaki, Shinji, Watanabe, Toshio, Ibi, Takayuki, Hasegawa, Kiyotoshi, Sakamoto, Yoichi, Moriwaki, Shunsuke, Kurogi, Kazuhito, Ogino, Atsushi, Yasumori, Takanori, Wakaguri, Hiroyuki, Muraki, Eiji, Miki, Youko, Yoshida, Yuichi, Inoue, Yoshinobu, Tabuchi, Ichiro, Iwao, Ken, Arishima, Taichi, Kawashima, Keisuke, Watanabe, Manabu, Sugano, Sumio, Sugimoto, Yoshikazu, Suzuki, Yutaka
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988166/
https://ncbi.nlm.nih.gov/pubmed/33758295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86225-y
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