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Loss of QKI in macrophage aggravates inflammatory bowel disease through amplified ROS signaling and microbiota disproportion

Inflammatory bowel disease (IBD) is a refractory chronic inflammatory illness of the gastrointestinal (GI) tract. Macrophage exerts an important role in IBD development. QKI, as an RNA binding protein, was related with inflammatory responses in bacterial infections by regulating the polarization of...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Wang, Wenwen, Zhai, Dongsheng, Bai, Yongquan, Xue, Ke, Deng, Lele, Ma, Lirong, Du, Tianshu, Ye, Zicheng, Qu, Di, Xiang, An, Chen, Guo, Zhao, Yi, Wang, Li, Lu, Zifan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988119/
https://ncbi.nlm.nih.gov/pubmed/33758177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00444-w
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