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Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1

Early acute kidney injury (AKI) contributes to severe morbidity and mortality in critically burned patients. Renal inflammation plays a vital role in the progression of early AKI, acting as a therapeutic target. Astaxanthin (ATX) is a strong antioxidant widely distributed in marine organisms that ex...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Guo, Songxue, Guo, Linsen, Fang, Quan, Yu, Meirong, Zhang, Liping, You, Chuangang, Wang, Xingang, Liu, Yong, Han, Chunmao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988001/
https://ncbi.nlm.nih.gov/pubmed/33758309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86146-w
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