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A Dual Systems Genetics Approach Identifies Common Genes, Networks, and Pathways for Type 1 and 2 Diabetes in Human Islets

Type 1 and 2 diabetes (T1/2D) are complex metabolic diseases caused by absolute or relative loss of functional β-cell mass, respectively. Both diseases are influenced by multiple genetic loci that alter disease risk. For many of the disease-associated loci, the causal candidate genes remain to be id...

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Publicat a:Front Genet
Autors principals: Kaur, Simranjeet, Mirza, Aashiq H., Overgaard, Anne J., Pociot, Flemming, Størling, Joachim
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987941/
https://ncbi.nlm.nih.gov/pubmed/33777101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.630109
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