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Alkaline brain pH shift in rodent lithium-pilocarpine model of epilepsy with chronic seizures

Brain pH is thought to be important in epilepsy. The regulation of brain pH is, however, still poorly understood in animal models of chronic seizures (SZ) as well as in patients with intractable epilepsy. We used chemical exchange saturation transfer (CEST) MRI to noninvasively determine if the pH i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brain Res
Hauptverfasser: Lu, Dongshuang, Ji, Yang, Sundaram, Padmavathi, Traub, Roger D., Guan, Yuguang, Zhou, Jian, Li, Tianfu, Sun, Phillip Zhe, Luan, Guoming, Okada, Yoshio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987840/
https://ncbi.nlm.nih.gov/pubmed/33556378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2021.147345
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