Characterization of Mice Ubiquitously Overexpressing Human 15-Lipoxygenase-1: Effect of Diabetes on Peripheral Neuropathy and Treatment with Menhaden Oil

To rigorously explore the role of omega-3 polyunsaturated fatty acids (PUFA) in the treatment of diabetic peripheral neuropathy (DPN), we have created a transgenic mouse utilizing a Cre-lox promoter to control overexpression of human 15-lipoxygenase-1 (15-LOX-1). In this study, we sought to determin...

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Vydáno v:J Diabetes Res
Hlavní autoři: Coppey, Lawrence, Obrosov, Alexander, Shevalye, Hanna, Davidson, Eric, Paradee, William, Yorek, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987465/
https://ncbi.nlm.nih.gov/pubmed/33816635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/5564477
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