Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells

RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator. Using live-cell super-resolution imaging, we can distinguish Hfq binding to different sizes of cellular RNAs. We demonstrate t...

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Veröffentlicht in:eLife
Hauptverfasser: Park, Seongjin, Prévost, Karine, Heideman, Emily M, Carrier, Marie-Claude, Azam, Muhammad S, Reyer, Matthew A, Liu, Wei, Massé, Eric, Fei, Jingyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Biochemistry and Chemical Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987339/
https://ncbi.nlm.nih.gov/pubmed/33616037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64207
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