The β3 Adrenergic Receptor Agonist CL316243 Ameliorates the Metabolic Abnormalities of High-Fat Diet-Fed Rats by Activating AMPK/PGC-1α Signaling in Skeletal Muscle

PURPOSE: Skeletal muscle has a major influence on whole-body metabolic homeostasis. In the present study, we aimed to determine the metabolic effects of the β3 adrenergic receptor agonist CL316243 (CL) in the skeletal muscle of high-fat diet-fed rats. METHODS: Sprague-Dawley rats were randomly alloc...

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Bibliografske podrobnosti
izdano v:Diabetes Metab Syndr Obes
Main Authors: Ding, Li-Na, Cheng, Ya, Xu, Lu-Yao, Zhou, Le-Quan, Guan, Li, Liu, Hai-Mei, Zhang, Ya-Xing, Li, Run-Mei, Xu, Jin-Wen
Format: Artigo
Jezik:Inglês
Izdano: Dove 2021
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7987271/
https://ncbi.nlm.nih.gov/pubmed/33776460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S297351
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