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Design, Synthesis, and Biological Evaluation of Chemically and Biologically Diverse Pyrroquinoline Pseudo Natural Products

Natural product (NP) structures are a rich source of inspiration for the discovery of new biologically relevant chemical matter. In natural product inspired pseudo‐NPs, NP‐derived fragments are combined de novo in unprecedented arrangements. Described here is the design and synthesis of a 155‐member...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Liu, Jie, Cremosnik, Gregor S., Otte, Felix, Pahl, Axel, Sievers, Sonja, Strohmann, Carsten, Waldmann, Herbert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986669/
https://ncbi.nlm.nih.gov/pubmed/33200868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013731
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