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Nonlinear ridge regression improves cell-type-specific differential expression analysis
BACKGROUND: Epigenome-wide association studies (EWAS) and differential gene expression analyses are generally performed on tissue samples, which consist of multiple cell types. Cell-type-specific effects of a trait, such as disease, on the omics expression are of interest but difficult or costly to...
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| Veröffentlicht in: | BMC Bioinformatics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7986289/ https://ncbi.nlm.nih.gov/pubmed/33752591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-03982-3 |
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