Systemic and topical administration of spermidine accelerates skin wound healing

BACKGROUND: The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA receptor (uPAR) signaling in vitro. Here, we inve...

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Dades bibliogràfiques
Publicat a:Cell Commun Signal
Autors principals: Ito, Daisuke, Ito, Hiroyasu, Ideta, Takayasu, Kanbe, Ayumu, Ninomiya, Soranobu, Shimizu, Masahito
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986284/
https://ncbi.nlm.nih.gov/pubmed/33752688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-021-00717-y
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