Efficacy and safety of iloprost in trauma patients with haemorrhagic shock‐induced endotheliopathy—Protocol for the multicentre randomized, placebo‐controlled, blinded, investigator‐initiated shine‐trauma trial

BACKGROUND: Traumatic injury accounts for 800 000 deaths in the European Union annually. The main causes of deaths in trauma patients are exsanguination and multiple organ failure (MOF). We have studied >1000 trauma patients and identified shock‐induced endotheliopathy (SHINE), the pathophysiolog...

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Vydáno v:Acta Anaesthesiol Scand
Hlavní autoři: Johansson, Pär I., Eriksen, Christian Fenger, Schmal, Hagen, Gaarder, Christine, Pall, Marlene, Henriksen, Hanne Hee, Bovbjerg, Pernille, Lange, Theis, Næss, Pål Aksel, Nielsen, Christian, Kirkegaard, Hans, Stensballe, Jakob
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Special Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986208/
https://ncbi.nlm.nih.gov/pubmed/33393084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aas.13776
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